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1

10.1038/16476

van Lohuizen, Maarten, Jacobs, Jacqueline J. L., Kieboom, Karin, Marino, Silvia, DePinho, Ronald A

Journal:

Year:

1999

Language:

english

File:

PDF, 488 KB

english, 1999

2

Bmi1 is essential for cerebellar development and is overexpressed in human medulloblastomas

Leung, Carly, Lingbeek, Merel, Shakhova, Olga, Liu, James, Tanger, Ellen, Saremaslani, Parvin, van Lohuizen, Maarten, Marino, Silvia

Journal:

Year:

2004

Language:

english

File:

PDF, 373 KB

english, 2004

3

Polycomb silencers control cell fate, development and cancer

Sparmann, Anke, van Lohuizen, Maarten

Journal:

Nature Reviews Cancer

Year:

2006

Language:

english

File:

PDF, 1.44 MB

english, 2006

4

Chromatin Position Effects Assayed by Thousands of Reporters Integrated in Parallel

Akhtar, Waseem, de Jong, Johann, Pindyurin, Alexey V., Pagie, Ludo, Meuleman, Wouter, de Ridder, Jeroen, Berns, Anton, Wessels, Lodewyk F.A., van Lohuizen, Maarten, van Steensel, Bas

Journal:

Year:

2013

Language:

english

File:

PDF, 8.90 MB

english, 2013

5

Transgenic mice as a means to study synergism between oncogenes

Anton Berns, Marco Breuer, Sjef Verbeek, Maarten Van Lohuizen

Journal:

International Journal of Cancer

Year:

1989

Language:

english

File:

PDF, 467 KB

english, 1989

6

The many faces of ubiquitinated histone H2A: insights from the DUBs

Joseph HA Vissers, Francesco Nicassio, Maarten van Lohuizen, Pier Paolo Di Fiore, Elisabetta Citterio

Journal:

Year:

2008

Language:

english

File:

PDF, 1.03 MB

english, 2008

7

Very high frequency of lymphoma induction by a chemical carcinogen in pim-1 transgenic mice

Breuer, Marco, Slebos, Robert, Verbeek, Sjef, van Lohuizen, Maarten, Wientjens, Ellen, Berns, Anton

Journal:

Year:

1989

File:

PDF, 382 KB

1989

8

Sequence similarity between the mammalian bmi-1 proto-oncogene and the Drosophila regulatory genes Psc and Su(z)2

van Lohuizen, Maarten, Frasch, Manfred, Wientjens, Ellen, Berns, Anton

Journal:

Year:

1991

File:

PDF, 508 KB

1991

9

Transformation of axial skeleton due to overexpression of bmi-1 in transgenic mice

Alkema, Mark J., van der Lugt, Nathalie M. T., Bobeldijk, René C., Berns, Anton, van Lohuizen, Maarten

Journal:

Year:

1995

File:

PDF, 580 KB

1995

10

Developmental biology: Two paths to silence merge

Taghavi, Panthea, van Lohuizen, Maarten

Journal:

Year:

2006

Language:

english

File:

PDF, 456 KB

english, 2006

11

Corrigendum: Genome-wide profiling of PRC1 and PRC2 Polycomb chromatin binding in Drosophila melanogaster

van Lohuizen, Maarten, Tolhuis, Bas, Muijrers, Inhua, de Wit, Elzo, Teunissen, Hans, Talhout, Wendy, van Steensel, Bas

Journal:

Nature Genetics

Year:

2006

Language:

english

File:

PDF, 187 KB

english, 2006

12

Genome-wide profiling of PRC1 and PRC2 Polycomb chromatin binding in Drosophila melanogaster

Tolhuis, Bas, Muijrers, Inhua, de Wit, Elzo, Teunissen, Hans, Talhout, Wendy, van Steensel, Bas, van Lohuizen, Maarten

Journal:

Nature Genetics

Year:

2006

Language:

english

File:

PDF, 379 KB

english, 2006

13

A high-throughput splinkerette-PCR method for the isolation and sequencing of retroviral insertion sites

Uren, Anthony G, Mikkers, Harald, Kool, Jaap, van der Weyden, Louise, Lund, Anders H, Wilson, Catherine H, Rance, Richard, Jonkers, Jos, van Lohuizen, Maarten, Berns, Anton

Journal:

Nature Protocols

Year:

2009

Language:

english

File:

PDF, 329 KB

english, 2009

14

Structure and E3-ligase activity of the Ring–Ring complex of Polycomb proteins Bmi1 and Ring1b

Buchwald, Gretel, van der Stoop, Petra, Weichenrieder, Oliver, Perrakis, Anastassis, van Lohuizen, Maarten, Sixma, Titia K

Journal:

The EMBO Journal

Year:

2006

Language:

english

File:

PDF, 431 KB

english, 2006

15

Perturbation of B and T cell development and predisposition to lymphomagenesis in EμBmi1 transgenic mice require the Bmi1 RING finger

Alkema, Mark J, Jacobs, Heinz, van Lohuizen, Maarten, Berns, Anton

Journal:

Year:

1997

Language:

english

File:

PDF, 552 KB

english, 1997

16

Tumurigenesis by slow-transforming retroviruses—an update

Maarten van Lohuizen, Anton Berns

Journal:

Biochimica et Biophysica Acta (BBA) - Reviews on Cancer

Year:

1990

Language:

english

File:

PDF, 2.52 MB

english, 1990

17

Bmi1 Controls Tumor Development in an Ink4a/Arf-Independent Manner in a Mouse Model for Glioma

Sophia W.M. Bruggeman, Danielle Hulsman, Ellen Tanger, Tessa Buckle, Marleen Blom, John Zevenhoven, Olaf van Tellingen, Maarten van Lohuizen

Journal:

Year:

2007

Language:

english

File:

PDF, 2.77 MB

english, 2007

18

Polycomb complexes and silencing mechanisms

Anders H Lund, Maarten van Lohuizen

Journal:

Current Opinion in Cell Biology

Year:

2004

Language:

english

File:

PDF, 187 KB

english, 2004

19

Stem cell regulation by polycomb repressors: postponing commitment

Alexandra M Pietersen, Maarten van Lohuizen

Journal:

Current Opinion in Cell Biology

Year:

2008

Language:

english

File:

PDF, 741 KB

english, 2008

20

Bmi1 Regulates Stem Cells and Proliferation and Differentiation of Committed Cells in Mammary Epithelium

Alexandra M. Pietersen, Bastiaan Evers, Asheeta A. Prasad, Ellen Tanger, Paulien Cornelissen-Steijger, Jos Jonkers, Maarten van Lohuizen

Journal:

Current Biology

Year:

2008

Language:

english

File:

PDF, 929 KB

english, 2008

21

Polycomb repression: from cellular memory to cellular proliferation and cancer

Jacqueline J.L. Jacobs, Maarten van Lohuizen

Journal:

Biochimica et Biophysica Acta (BBA) - Reviews on Cancer

Year:

2002

Language:

english

File:

PDF, 227 KB

english, 2002

22

RUNX: A trilogy of cancer genes

Anders H Lund, Maarten van Lohuizen

Journal:

Year:

2002

Language:

english

File:

PDF, 83 KB

english, 2002

23

Physical and functional interaction between PML and TBX2 in the establishment of cellular senescence

Martin, Nadine, Benhamed, Moussa, Nacerddine, Karim, Demarque, Maud D, van Lohuizen, Maarten, Dejean, Anne, Bischof, Oliver

Journal:

The EMBO Journal

Year:

2011

Language:

english

File:

PDF, 1.57 MB

english, 2011

24

MPc2, a new murine homolog of the Drosophila polycomb protein is a member of the mouse polycomb transcriptional repressor complex

Mark J Alkema, Jacqueline Jacobs, Jan Willem Voncken, Nancy A Jenkins, Neal G Copeland, David P.E Satijn, Arie P Otte, Anton Berns, Maarten van Lohuizen

Journal:

Journal of Molecular Biology

Year:

1997

Language:

english

File:

PDF, 825 KB

english, 1997

25

Cellular memory of transcriptional states by Polycomb-group proteins

Jacqueline J.L. Jacobs, Maarten van Lohuizen

Journal:

Seminars in Cell & Developmental Biology

Year:

1999

Language:

english

File:

PDF, 234 KB

english, 1999

26

Bmi1 deficient neural stem cells have increased Integrin dependent adhesion to self-secreted matrix

Sophia W.M. Bruggeman, Danielle Hulsman, Maarten van Lohuizen

Journal:

Biochimica et Biophysica Acta (BBA) - General Subjects

Year:

2009

Language:

english

File:

PDF, 918 KB

english, 2009

27

Stem Cells and Cancer: The Polycomb Connection

Merel E. Valk-Lingbeek, Sophia W.M. Bruggeman, Maarten van Lohuizen

Journal:

Year:

2004

Language:

english

File:

PDF, 157 KB

english, 2004

28

Polycomb Group Proteins Ezh2 and Rnf2 Direct Genomic Contraction and Imprinted Repression in Early Mouse Embryos

Rémi Terranova, Shihori Yokobayashi, Michael B. Stadler, Arie P. Otte, Maarten van Lohuizen, Stuart H. Orkin, Antoine H.F.M. Peters

Journal:

Developmental Cell

Year:

2008

Language:

english

File:

PDF, 1.18 MB

english, 2008

29

Differentiation and gene regulation: Genomic programs and differentiation

Vincenzo Pirrotta, Maarten van Lohuizen

Journal:

Current Opinion in Genetics & Development

Year:

2006

Language:

english

File:

PDF, 98 KB

english, 2006

30

Enhanced Self-Renewal of Hematopoietic Stem Cells Mediated by the Polycomb Gene Product Bmi-1

Atsushi Iwama, Hideyuki Oguro, Masamitsu Negishi, Yuko Kato, Youhei Morita, Hiroko Tsukui, Hideo Ema, Takehiko Kamijo, Yuko Katoh-Fukui, Haruhiko Koseki, Maarten van Lohuizen, Hiromitsu Nakauchi

Journal:

Year:

2004

Language:

english

File:

PDF, 411 KB

english, 2004

31

Thymocyte Proliferation Induced by Pre-T Cell Receptor Signaling Is Maintained through Polycomb Gene Product Bmi-1-Mediated Cdkn2a Repression

Masaki Miyazaki, Kazuko Miyazaki, Manami Itoi, Yuko Katoh, Yun Guo, Rieko Kanno, Yuko Katoh-Fukui, Hiroaki Honda, Takashi Amagai, Maarten van Lohuizen, Hiroshi Kawamoto, Masamoto Kanno

Journal:

Year:

2008

Language:

english

File:

PDF, 2.21 MB

english, 2008

32

Molecular Maps of the Reorganization of Genome-Nuclear Lamina Interactions during Differentiation

Daan Peric-Hupkes, Wouter Meuleman, Ludo Pagie, Sophia W.M. Bruggeman, Irina Solovei, Wim Brugman, Stefan Gräf, Paul Flicek, Ron M. Kerkhoven, Maarten van Lohuizen, Marcel Reinders, Lodewyk Wessels, B

Journal:

Year:

2010

Language:

english

File:

PDF, 1.54 MB

english, 2010

33

Functional Crosstalk between Bmi1 and MLL/Hoxa9 Axis in Establishment of Normal Hematopoietic and Leukemic Stem Cells

Lan-Lan Smith, Jenny Yeung, Bernd B. Zeisig, Nikolay Popov, Ivo Huijbers, Josephine Barnes, Amanda J. Wilson, Erdogan Taskesen, Ruud Delwel, Jesús Gil, Maarten Van Lohuizen, Chi Wai Eric So

Journal:

Year:

2011

Language:

english

File:

PDF, 1.74 MB

english, 2011

34

The Polycomb group — no longer an exclusive club?

Hugh W Brock, Maarten van Lohuizen

Journal:

Current Opinion in Genetics & Development

Year:

2001

Language:

english

File:

PDF, 135 KB

english, 2001

35

The trithorax-group and Polycomb-group chromatin modifiers: implications for disease

Maarten van Lohuizen

Journal:

Current Opinion in Genetics & Development

Year:

1999

Language:

english

File:

PDF, 888 KB

english, 1999

36

Bmi-1 Regulation of INK4A-ARF Is a Downstream Requirement for Transformation of Hematopoietic Progenitors by E2a-Pbx1

Kevin S. Smith, Sumit K. Chanda, Merel Lingbeek, Douglas T. Ross, David Botstein, Maarten van Lohuizen, Michael L. Cleary

Journal:

Year:

2003

Language:

english

File:

PDF, 324 KB

english, 2003

37

Interactions among Polycomb Domains Are Guided by Chromosome Architecture

Tolhuis, Bas, Blom, Marleen, Kerkhoven, Ron M., Pagie, Ludo, Teunissen, Hans, Nieuwland, Marja, Simonis, Marieke, de Laat, Wouter, van Lohuizen, Maarten, van Steensel, Bas, Bickmore, Wendy A.

Journal:

Year:

2011

Language:

english

File:

PDF, 2.04 MB

english, 2011

38

Chromosome conformation capture on chip in single Drosophila melanogaster tissues

Bas Tolhuis, Marleen Blom, Maarten van Lohuizen

Journal:

Year:

2012

Language:

english

File:

PDF, 1.49 MB

english, 2012

39

10.1038/81583

van Lohuizen, Maarten, Jacobs, Jacqueline J.L., Keblusek, Petra, Robanus-Maandag, Els, Kristel, Petra, Lingbeek, Merel, Nederlof, Petra M., van Welsem, Tibor, van de Vijver, Marc J., Koh, Eugene Y., D

Journal:

Nature Genetics

Year:

2000

Language:

english

File:

PDF, 661 KB

english, 2000

40

Genome-wide retroviral insertional tagging of genes involved in cancer in Cdkn2a-deficient mice

Lund, Anders H., Turner, Geoffrey, Trubetskoy, Alla, Verhoeven, Els, Wientjens, Ellen, Hulsman, Danielle, Russell, Robert, DePinho, Ronald A., Lenz, Jack, van Lohuizen, Maarten

Journal:

Nature Genetics

Year:

2002

Language:

english

File:

PDF, 406 KB

english, 2002

41

Identification of cooperating oncogenes in Eμ-myc transgenic mice by provirus tagging

Maarten van Lohuizen, Sjef Verbeek, Blanca Scheljen, Ellen Wientjens, Hanneke van der Guidon, Anton Berns

Journal:

Year:

1991

Language:

english

File:

PDF, 3.36 MB

english, 1991

42

509 The polycomb group protein BMI-1 is a novel T cell antigen in human hepatocellular carcinoma

David H. Adams, Elizabeth Torr, Jane Steele, Maarten van Lohuizen, Gary M. Raynolds, Stefan G. Hubscher, Lawrence S. Young

Journal:

Year:

2003

Language:

english

File:

PDF, 148 KB

english, 2003

43

PRC1 coordinates timing of sexual differentiation of female primordial germ cells

Yokobayashi, Shihori, Liang, Ching-Yeu, Kohler, Hubertus, Nestorov, Peter, Liu, Zichuan, Vidal, Miguel, van Lohuizen, Maarten, Roloff, Tim C., Peters, Antoine H. F. M.

Journal:

Year:

2013

Language:

english

File:

PDF, 1.06 MB

english, 2013

44

In Vivo RNAi Screen for BMI1 Targets Identifies TGF-β/BMP-ER Stress Pathways as Key Regulators of Neural- and Malignant Glioma-Stem Cell Homeostasis

Gargiulo, Gaetano, Cesaroni, Matteo, Serresi, Michela, de Vries, Nienke, Hulsman, Danielle, Bruggeman, Sophia W., Lancini, Cesare, van Lohuizen, Maarten

Journal:

Year:

2013

Language:

english

File:

PDF, 5.83 MB

english, 2013

45

Bmi1 Is Required for Hedgehog Pathway-Driven Medulloblastoma Expansion

Michael, Lowell Evan, Westerman, Bart A., Ermilov, Alexandre N., Wang, Aiqin, Ferris, Jennifer, Liu, Jianhong, Blom, Marleen, Ellison, David W., van Lohuizen, Maarten, Dlugosz, Andrzej A.

Journal:

Year:

2008

Language:

english

File:

PDF, 2.20 MB

english, 2008

46

Predisposition to lymphomagenesis in pim-1 transgenic mice: Cooperation with c-myc and N-myc in murine leukemia virus-induced tumors

van Lohuizen, Maarten, Verbeek, Sjef, Krimpenfort, Paul, Domen, Jos, Saris, Chris, Radaszkiewicz, Thaddeus, Berns, Anton

Journal:

Year:

1989

Language:

english

File:

PDF, 2.29 MB

english, 1989

47

In vivo shRNA screens in solid tumors

Gargiulo, Gaetano, Serresi, Michela, Cesaroni, Matteo, Hulsman, Danielle, van Lohuizen, Maarten

Journal:

Nature Protocols

Year:

2014

Language:

english

File:

PDF, 2.10 MB

english, 2014

48

Characterization and chromosomal localization of the human proto-oncogene BMI-1

Alkema, Mark, Wiegant, Joop, Raap, Anton K., Bems, Anton, van Lohuizen, Maarten

Journal:

Human Molecular Genetics

Year:

1993

Language:

english

File:

PDF, 5.35 MB

english, 1993

49

Prolonged Ezh2 Depletion in Glioblastoma Causes a Robust Switch in Cell Fate Resulting in Tumor Progression

de Vries, Nienke A., Hulsman, Danielle, Akhtar, Waseem, de Jong, Johann, Miles, Denise C., Blom, Marleen, van Tellingen, Olaf, Jonkers, Jos, van Lohuizen, Maarten

Journal:

Year:

2015

Language:

english

File:

PDF, 6.43 MB

english, 2015

50

109: In vivo RNAi for target validation in oncology

Jost, Seibler, Ewa, Michalak, Karim, Nacerddine, Maarten, van Lohuizen, Jos, Jonkers

Journal:

Bulletin du Cancer

Year:

2010

Language:

english

File:

PDF, 46 KB

english, 2010